4-Fluoro-1H-pyrrolo[2,3-B]pyridin-2(3H)-one
4-Fluoro-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one
CAS: 956460-93-8
Molecular Formula: C7H5FN2O
4-Fluoro-1H-pyrrolo[2,3-B]pyridin-2(3H)-one - Names and Identifiers
4-Fluoro-1H-pyrrolo[2,3-B]pyridin-2(3H)-one - Physico-chemical Properties
| Molecular Formula | C7H5FN2O |
| Molar Mass | 152.13 |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
4-Fluoro-1H-pyrrolo[2,3-B]pyridin-2(3H)-one - Introduction
4-Fluoro-1,3-dihydro-pyridin-2-one, also known as 4-Fluoro-1,3-dihydro-pryrrolo [2,3-b]pyridin-2-one, is an organic compound. Its molecular formula is C6H4FN3O and its structural formula is:
It has the following properties:
1. Appearance: white crystal or crystalline powder
2. Melting point: about 180-185°C
3. Solubility: It is more soluble in polar solvents such as chloroform, dimethyl sulfoxide and dichloromethane.
4-Fluoro-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one is mainly used in organic synthesis and pharmaceutical research. It is widely used in the pharmaceutical field as an inhibitor of interferon signal transduction, an antitumor drug and an intermediate of antiviral drugs.
The method of preparing 4-Fluoro-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one includes synthesis from known compounds by multi-step synthesis, which includes the steps of copper-catalyzed cyanation reaction of 5-substituted pyridine, acetylene deprotection reaction, amidation and ketonization.
When using 4-Fluoro-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one, you need to pay attention to the following safety information:
1. Avoid inhalation, contact with skin and ingestion. Appropriate personal protective equipment such as gloves, safety glasses and protective clothing should be worn.
2. Avoid contact with strong oxidants and strong acids to avoid dangerous reactions.
3. Store in a dry, cool, ventilated place, away from fire and heat sources.
4. If contact occurs, rinse the skin with plenty of water and seek medical attention if necessary. If inhaled or ingested by mistake, seek medical attention immediately.
It has the following properties:
1. Appearance: white crystal or crystalline powder
2. Melting point: about 180-185°C
3. Solubility: It is more soluble in polar solvents such as chloroform, dimethyl sulfoxide and dichloromethane.
4-Fluoro-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one is mainly used in organic synthesis and pharmaceutical research. It is widely used in the pharmaceutical field as an inhibitor of interferon signal transduction, an antitumor drug and an intermediate of antiviral drugs.
The method of preparing 4-Fluoro-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one includes synthesis from known compounds by multi-step synthesis, which includes the steps of copper-catalyzed cyanation reaction of 5-substituted pyridine, acetylene deprotection reaction, amidation and ketonization.
When using 4-Fluoro-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one, you need to pay attention to the following safety information:
1. Avoid inhalation, contact with skin and ingestion. Appropriate personal protective equipment such as gloves, safety glasses and protective clothing should be worn.
2. Avoid contact with strong oxidants and strong acids to avoid dangerous reactions.
3. Store in a dry, cool, ventilated place, away from fire and heat sources.
4. If contact occurs, rinse the skin with plenty of water and seek medical attention if necessary. If inhaled or ingested by mistake, seek medical attention immediately.
Last Update：2024-04-09 19:05:53
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Product Name: 4-Fluoro-1H-pyrrolo[2,3-b... Visit Supplier Webpage Request for quotation
CAS: 956460-93-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 956460-93-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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